In: Science

Submitted By shetu145
Words 298
Pages 2
Seachange Technology plan to release an eco-friendly shark repellent device which will be known as the Scuba Shark Shield, a promotional image can be seen on the report title page.

Our goal is to achieve 100% customer satisfaction so our focus will be on product quality; the Shark Shield will never fail (excluding battery life). We will be the first company to enter this specific industry so to take advantage of our first mover advantage we will do substantial promotion to gain maximum market share before any competitors arise.

Our demographic is mainly middle-aged with above average income and they spend on average $1300 per year in scuba diving and they prefer quality over value. After conducting a survey it was found that 50% of scuba divers would either definitely buy or possibly buy the Shark Shield. We will be advertising the quality of our product and our target market share is 30% of scuba divers after 5 years.

The sale price of the Shark Shield is $750 including $600 in expenses and a $150 (25%) markup. Underwater camera, underwater propulsion devices and some drysuits cost $2000+ and having the target audience prefer quality over value we expect the audience won’t perceive the price as too high.

The capital we require to start the project is $840,000 which covers all initial development expenses, ongoing expenses will be covered by sales. The loan will be paid off over a 5 year period.

Our expected market share will grow most rapidly in the first 5 years then stabilize after 8 to 10 years. Our promotion strategy includes: direct mail, magazine advertisements, website advertisements, sponsorship and affiliation.

Quality is our primary concern so we will be implementing quality control systems including: audits, documentation and meeting Australian regulatory…...

Similar Documents


...cholesterol in blood. It belongs to a class of drugs referred to as statins, thus Lipitor is classified as a drug (Smith and Knapp, 1972). This research was intended to best understand the drug Lipitor. How it works and generally gets some vital information about the drug so that at the end of this research I can have a vivid understanding of its expected effects. Materials and methods This research was done by going through medical books and online journals medical articles. I also requested for clarification from Medical personnel who were of so much help as far as how the drug generally works is concerned and its side effects. I interviewed some patients that were under Lipitor dosage and also patients that have been treated using Lipitor dosage before. I also got information from the information printed on its pack. Results In my research I found out that The main ingredient in Lipitor is a chemical known as atorvastatin which is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme(Roberts, 2012). This enzyme catalyzes the conversion of HMG-CoA to mevalonate is catalyzed by this enzyme which in cholesterol biosynthesis is an early and rate-limiting step. Atorvastatin calcium has an empirical formula of (C33H34FN2O5)2Ca•3H2O with a molecular weight of 1208.43. (Webster, 2009). Discussion Atorvastatin which is the main ingredient in Lipitor works to lower cholesterol levels just like all other statins. It can also be said that Lipitor competitively inhibits HMG-CoA......

Words: 1065 - Pages: 5

Communication we can't turn back the clock: Age is a huge risk factor for cardiovascular disease. Being a man early in life is a risk factor for heart disease, which certainly is not changeable. And then the third thing is that we can't choose our parents. Family history is a risk factor for cardiovascular disease. ANNOUNCER: Different medications can be prescribed to help prevent or control cardiovascular disease ADOLPH M. HUTTER, Jr., MD: There are a number of medications that are actually very effective in preventing heart attacks and other forms of atherosclerosis. One is the simple drug aspirin. Aspirin has been shown to reduce strokes in women and heart attacks in men. Another very important class of drugs are the drugs called statins. The statins are drugs that lower the bad cholesterol, the LDL. They lower it very effectively, and many studies have shown that these drugs can prevent the onset of heart disease and the progression of heart disease if you already have it. A class of drugs called beta blockers can be very effective in protecting people who have already had a heart attack. They're also helpful in controlling blood pressure and controlling angina, which is a symptom of chest discomfort due to a blockage in the artery. ANNOUNCER: It is also crucial that a patient makes lifestyle modifications. ADOLPH M. HUTTER, Jr., MD: Heart disease is very preventable. You must absolutely stop smoking. You must have a low cholesterol, particularly the low bad......

Words: 517 - Pages: 3

My Personal Property

...Drug Study Atorvastatin(lipitor) fourty mg one tablet once a day at HS eight pm DRUG CLASS AND MECHANISM: Atorvastatin is an oral drug that lowers the level of cholesterol in the blood. It belongs to a class of drugs referred to as statins, which includes lovastatin (Mevacor), simvastatin, (Zocor), fluvastatin (Lescol), and pravastatin (Pravachol) and rosuvastatin (Crestor). All statins, including atorvastatin, prevent the production of cholesterol in the liver by blocking HMG-CoA reductase, an enzyme that makes cholesterol. Statins reduce total cholesterol as well as LDL cholesterol in blood. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease. Reducing LDL cholesterol levels retards progression and may even reverse coronary artery disease. Atorvastatin also raises the concentrations of HDL ("good") cholesterol that protects against coronary artery disease and reduces the concentration of triglycerides in the blood. Indications Reduce risk of stroke & heart attack in type 2 diabetes patients without evidence of heart disease but with other risk CV factors Reduce risk of stroke, heart attack and revascularizations procedures in patients without evidence of coronary heart disease (CHD) but with multiple risk factors other than diabetes (eg, smoking, HTN, low HDL-C, family history of early CHD) Patients with CHD to reduce risks of MI, stroke, revascularization procedures,......

Words: 532 - Pages: 3


...imaging for composition and anatomical sites of the vascular wall. However, there are some limitations for these techniques such as when the plaques are small; the camera has inappropriate resolution; and when the target is in the motion state, which makes the snapshot very difficult (Laitinen, 2009). Intracoronary angioscopy Intracoronary angioscopy is a technique used to detect the plaque characteristics inside the artery. The technique has the ability to determine if there is a thrombus in the arterial lumen using special optical fibers. Also it provides a clear color image to the plaque morphology and stability in the luminal surface. Interestingly, the technique is considered to be a therapeutic tool, and can applied to people who take statin to lower the lipid concentration in the blood to CURRENT DIAGNOSIS AND TREATMENT OF ATHEROSCLEROSIS 12 demonstrate the changes in the plaque color. However, angioscopy has some drawbacks, like it needs a free blood stream and it is limited to a specific part of the artery (Van Velzen, 2009). Prevention and Treatment of the atherosclerosis Life style changes The prevention program should start in the early ages, especially, for people who are at risk of non- modifiable risk factors like (aging and family history). Asymptomatic patients should also be properly monitored, especially for the modifiable risk factors in order to decrease the incidence of developing the disease. People who are suffering from atherosclerosis......

Words: 4999 - Pages: 20

Cholesterol Synthesis

...3-hydroxy-3-methylglutaryl CoA (HMG CoA) from acetyl CoA. * Initially, two molecules of acetyl-CoA condense to form Acetoacetyl-CoA catalyzed by cytosolic thiolase. * Acetoacetyl-CoA condenses with a further molecule of acetyl-CoA catalyzed by HMG-CoA synthase to form HMG-CoA, that is reduced to mevalonate by NADPH catalyzed by HMG-CoA reductase. * * The synthesis of mevalonate is the committed step in cholesterol formation. * The enzyme catalyzing this irreversible step, * 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase), is an important control site in cholesterol biosynthesis, * and is the site of action of the most effective class of cholesterol-lowering drugs, the HMG-CoA reductase inhibitors (statins). Mevalonate is converted into 3-isopentenyl pyrophosphate in three consecutive reactions requiring ATP. * Decarboxylation yields Isopentenyl pyrophosphate, an activated isoprene unit that is a key building block for many important biomolecules. Stage 2:: SYNTHESIS OF SQUALENE * Squalene (C30) is synthesized from six molecules of Isopentenyl Pyrophosphate (C5) and the reaction sequence is- * C5 C10 C15 C30 * This stage in the synthesis of cholesterol starts with the isomerization of isopentenyl pyrophosphate to dimethylallyl pyrophosphate. * Isopentenyl diphosphate is isomerized by a shift of the double bond to form dimethylallyl diphosphate, then condensed with another molecule of isopentenyl......

Words: 1847 - Pages: 8


...the decline in demand for enzymes, Biocon starting developing its growth strategy into other markets. They recognized the increased demand for outsourced R&D in the pharmaceutical sector and created a subsidiary, Syngene International, in 1994 to develop globally competitive process technology. The company also identified the biopharmaceutical market and generic drugs as their entry point to produce pharmaceuticals. They decided to leverage their fermenting expertise to produce generic pharma molecules. In 2001, after gaining independence from Unilever, Bicon began to develop and establish its brand positioning. It became the first company to be approved by the U.S. to manufacture statins that could be distributed in the U.S., eventually gaining a 15% to 20% U.S. market share. But when Statins’ prices started to wane, Biocon, remaining true to its growth strategy, entered the higher-price-fetching insulin market. Their brand positioning worked well for them as they were the only Bio-tech company that could meet India’s market demand. The company simultaneously developed its marketing strategy and skills from scratch. Also the point-of-difference with their only competitors in India, Novo and Eli Lily, was the 20% to 30% price difference in favor of Biocon. They quickly gained 10% of the Indian market and 25% to 30% of new insulin prescriptions. Anticipating the maturing of the Indian drug market, Bicon developed its growth strategy further. This time they shifted their......

Words: 381 - Pages: 2


...from a professional resource. Zetia is a drug that is prescribed to about 1 million people a week for the purpose of lowering cholesterol (Berenson, 2008). According to the article, the drug company Merck and Schering-Plough had stated that Zetia has failed to show any medical benefits (Berenson, 2008). The information to be presented is going to be about the drug Zetia (ezetimibe) and Zocor (simvastatin) combined and is called Vytorin. Discussion Zetia is a newer cholesterol drug that works by blocking the cholesterol in food from crossing the intestinal wall and getting into the bloodstream (Ijioma & Robinson, 2011). Statins prevent cholesterol from being absorbed in the liver, and also reduce inflammation, another cause of cardiovascular disease. Adding Zetia to a statin cuts cholesterol levels much more than just increasing the dose of the statin. Vytorin is a combo pill; it combines simvastatin, which blocks production of cholesterol in the liver, and ezetimibe, which blocks absorption of cholesterol in the intestines (Ijioma & Robinson, 2011). Vytorin is indicated for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments or if such treatments are unavailable (RxList, nd). The New York Times and the professional article both talk about the effects of Zetia. The lay article states that Zetia lowers cholesterol by 15 – 20 percent in most patients, but no......

Words: 792 - Pages: 4

Cholesterol Guidelines

...Americans will have a new CAD event and approximately 470,000 will have a recurrent attack. The cost of CAD is astounding and is estimated at $172 billion annually (Heidenreich, el. al., 2011). Cardiovascular disease (CVD) is the leading cause of death in the United States (US) and is responsible to 17% of the national health expenditures. It has been eight years since new cholesterol guidelines have been updated and the new guidelines have created a little controversy. The ATP IV guidelines set by the American College of Cardiology/American Heart Association (ACC/AHA) have created many waves in the treatment of cholesterol and lipid management. The guidelines stress the prevention of stroke as well as heart disease and focuses on statin therapy rather than other alternative unproven therapeutic agents. It also recognizes that more intensive treatment is superior to less intensive treatment for many patients. History Cholesterol screening guidelines have evolved and changed over the past couple of years, but there continues to be gaps in care with an insufficient number of patients receiving standard of care with lipid-lowering therapy. The numerous guidelines set out by specialty practices have been shown to be a contributing factor to suboptimal management of cholesterol management. The new ATP IV guidelines established by the ACC/AHA have sparked considerable controversy from the previous ATP III guidelines and many professional organizations are not......

Words: 2310 - Pages: 10

Review of Article: “Statin Use and Risk of Cerebral Aneurysm Rupture: a Hospital-Based Case-Control Study in Japan, ” Y. Yoshimura, Y. Murakami, Et Al.

...Review of article: “Statin Use and Risk of Cerebral Aneurysm Rupture: A Hospital-based Case-control Study in Japan,” Y. Yoshimura, Y. Murakami, et al. Design and Data Collection The presented study is a case-control study design, meaning it is based on measuring the associations between statin administration and the likely rupture of a cerebral aneurysm in purposefully selected indicator and control populations. The foundation of the study grew from theoretical components tied to animal models used in the past. The underlying conditions of interest are important but not commonly seen in humans, making it difficult to know the best medical measurements and, if possible, prescriptive interventions for unruptured neurological disorders, which generally now can be dealt with by way of surgical interventions. The written assessment of the study indicated limited evidence of human studies showing the effect of statin drugs in reducing the risk of aneurysmal ruptures. The study model used in this investigation (case-control) is readily suitable to study uncommon diseases with low overall prevalence rates. However, given the impact such a condition could have on a population segment thought to have many years of productivity – and because of promising animal studies – the study was deemed beneficial as an initial step toward learning more about the drug’s beneficial indicators. The primary endpoint of focus was the likelihood of the rupture of an aneurism and the protective......

Words: 5143 - Pages: 21

Data to Knowledge

...obesity) in at least 38% (Roger, et al., 2012). The presence of peripheral arterial or carotid disease detected during community cardiovascular screening changes risk stratification. Evidence-based treatment guidelines, such as aspirin and statin use can be implemented in those with risk factors to minimize the risk of a life threatening or debilitating health event such as myocardial infarction or stroke. The Dare to Care (DTC) program is a community cardiovascular screening program that utilizes ultrasound to screen for carotid atherosclerosis and abdominal aneurysm, in addition to peripheral arterial disease, hypertension (HTN), and self-report risk factor assessment. A clinical question of interest: How effective is a community cardiovascular screening program in identifying persons with subclinical atherosclerosis, who are at risk and not on appropriate preventative treatments such as aspirin and statins? The purpose of this paper is to identify potential data sources, discuss data access implications, and identify strengths and weaknesses of data sets and identity potential data analysis testing tools. Potential Data Sources The DTC program utilizes an old FoxPro SQL database to enter screening results, risk factors, anti-platelet and statin use, and risk assessment categorization for each participant. This information can be electronically downloaded into an excel worksheet for data analysis. Specific data elements of interest include: demographics; presence of......

Words: 1475 - Pages: 6

Novo Industry

...drugs still the common solution to the problem? As the article points out, a solution doctors often use when a patients LDL level is too high is to put him or her on a drug that belongs to a group called statins. The best-selling of the statins is atorvastatin, marketed as Lipitor. By 2003 it had become the best-selling pharmaceutical in history (CNN,Simons). This cholesterol-lowering drug, remains the best-selling drug in America in 2011 (Forbes,Herper). So it’s not hard too see the financial motivation for continuing to distribute the drug, even if it doesn’t fix the root of the problem. The root of the problem with heart disease is that the blood arteries get narrowed. Like this article suggests. This surely does not happen solely because of eating cholesterol rich foods, like many people believe. Smoking or using tobacco is one of the most significant risk factors for developing heart disease. Chemicals in tobacco can damage your heart and blood vessels, leading to narrowing of the arteries (Mayo Clinic). A 10-year study of 25,000 men found that guys who were entirely unfit had the highest risk of heart attack, regard less of their cholesterol numbers. Ultimately, a healthier diet may be one of the best weapons against heart disease - better than taking statins, as statins attempt to fix a the LDL level, which is a symptom if heart desease, and not the real cause. Sources: 1. UCLA Newsroom.......

Words: 733 - Pages: 3

Case Study in Ineffective Pharmacological Management

...according to which types of lipids are elevated, that is hypercholesterolemia, Hypertriglyceridemia or both combined hyperlipidemia. Elevated levels of Lipoprotein (a) may also be classified as a form of hyperlipidemia. For treatment of type II, dietary modification is the initial approach, but many patients require treatment with statins (HMG-CoA reductase inhibitors) to reduce cardiovascular risk. If the triglyceride level is markedly raised, fibrates (peroxisome proliferator-activated receptor-alpha agonists) may be preferable due to their beneficial effects, Combination treatment of statins and fibrates, while highly effective, causes a markedly increased risk of myopathy and rhabdomyolysis, so is only done under close supervision. Other agents commonly added to statins are ezetimibe, niacin, and bile acid sequestrates. Dietary supplementation with fish oil is also used to reduce elevated triglycerides, with the greatest severity. Some evidence exists for benefit of plant sterol-containing products and omega-3 fatty acids. The National Cholesterol Education Program-Adult Treatment Panel IV treatment recommendations attempt to identify four Statin groups that are based on 4 questions: 1. Does the patient have a history of heart disease or stroke? (Use 2011 AHA/ACC secondary prevention guidelines). Mr. J.S. does have a history of heart disease and stroke. 2. Is LDL> 190 mg/dL? They have FH. Mr. J’s LDL was 200. Do not know if there was a family history. 3. Does patient......

Words: 4958 - Pages: 20


...symptoms and her future health. 11. To whom it may concern (or Dr. Yada Yada), I have tested and reviewed Ms. Yetter’s cholesterol and have provided copies of the results. As per the diagnosis, I suggest developing a diet that is consistent to improve her quality of life and to begin a medication regimen that would assist her in reaching her goals. Just as well, I suggest evaluating her medication profile once again and determining if these medications are best for her. I would also suggest motivating Ms. Yetter to quit smoking and exercise because she is on the verge of stage 1 obesity. If you have any questions, please feel free to give me a call. Vikas Jain, Pharm.D. 12. I would tell her that the new prescription is a good statin aimed at decreasing her cholesterol when used appropriately with a developed diet. Also, I would explain which of her cholesterol numbers are high and what that could impact in her daily life, if not now then later. I would again stress the importance of medication compliance and lifestyle changes if that hasn’t already happened. 13. Ms. Yetter’s risk category is moderate but is close to the edge of moderately high. She can easily cross this line if she does not begin making some changes in her daily lifestyle. 14. Ms. Yetter’s goal for LDL should be to be below 130, but I would suggest her to be below 100. This is because she is moderate currently, but because she is close to moderately high, it would be better if she went the......

Words: 1462 - Pages: 6

Statins Use

...the change from treating target levels or lab tests to treatment based on risk level and intensity of statin therapy. They identified 4 groups that would likely benefit from statin therapy: * History of arteriosclerotic cardiovascular disease (ASCVD) * LDL- cholesterol >190 mg/dl * Between 40-75 years of age with history of diabetes * Between 40-75 year of age and a 10-year ASVD Risk > 7.5% A second key difference is lack of LDL goals in order to monitor the effectiveness of cholesterol lowering medications. There were no recommendations made on follow up LDL testing, which differs from previous guidelines. The best way to accomplish the AHA/ACC recommended goals is to focus on decreasing cardiovascular disease events or ASCVD. Another major change to the guidelines states that non-statin therapies do not provide acceptable ASCVD risk reduction benefits compared to their potential for adverse effects. This recommendation will decrease the amount of non- statin medication being used for treatment. Another change made by the ACC/AHA was utilization of a pooled cohort risk assessment instead of the Framingham Risk Calculator to estimate 10-year risks for a patient to develop ASCVD. Based on the new lipid guidelines established by the ACC/AHA, patients with an elevated ASCVD risk of (≥7.5) would benefit from either a high-intensity or moderate-intensity statin. The patient in the case study had an ASCVD risk of 8.7%. Revisiting this patient’s case we......

Words: 841 - Pages: 4

Identification of Statins in Rice Fermented with Monascus Species from the Museum of Natural History

...IDENTIFICATION OF STATINS IN RICE FERMENTED WITH MONASCUS SPECIES FROM THE MUSEUM OF NATURAL HISTORY Jude Carlo J. Muca1, Reigna S. Romero1, Ricardo R. Santos², Roberto Z. Yuseco3, Florence M. Blanco1, Lei Anne C. Carolino1, Engkhuan Chew1, Ericka Joy B. De Guzman1, Jordan Carlo S. Galang1, Jin-Gu Lee1, Lawrence Y. Maliwat1, Marixie Ann Q. Manarang1, Jeshua Caleb B. Miole1, Michael Henry B. Piano1, Lou Anthony S. Sico1, Mark Lester I. Tolenada1, Mellanie B. Victoria1 1 Medical Student, Angeles University Foundation, Angeles City 2009; ²Head, Department of Biochemistry, School of Medicine, Angeles University Foundation, Angeles City 2009; 3 Faculty, Department of Biochemistry, School of Medicine, Angeles University Foundation, Angeles City 2009; ABSTRACT Pharmaceutical intervention through statin drugs is the most common way of slowing down the adverse effects of heart disease due to cholesterol deposition by regulating the activity of HMG-CoA reductase which catalyzes conversion of HMG-CoA to mevalonate. In order to seek alternatives for commercially available statin drugs, this study idnetified the statins that can be produced by fermentation of rice by Monascus strains available at the Museum of Natural History (MNH). It also shall serve as a set-off point for further studies regarding the use of fermentation products for treatment of certain ailments, such as heart disease. A total of eight (8) isolates available at the Museum of Natural History (MNH) of the......

Words: 3052 - Pages: 13

Animowane | A Saga Crepúsculo – Amanhecer Parte 1 1080p Dublado – Torrent Download (2011) | Demand Supply