Study Sheet

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Study sheet
Functions of inflammatory response
1.Prevents the spread of the injurious agent to nearby tissue
2.Disposes of cellular debris and pathogens
3.Sets the stage for repair process
4.Neutrophils and other WBCs are attracted to inflammatory site by chemotaxis
Class of antibodies
IgM
First antibody released; potent agglutinating agent; cause other immune system cells to destroy foreign substances
IgA
Found in nose, breathing passages, digestive tract, ears, eyes & vagina. In mucous and other secretions; helps prevent entry of pathogens
IgD
Monomer attached to surface of B cells (receptor); found in tissues that line belly and chest.
IgG
75-85% of plasma antibodies; crosses placental barrier to help protect fetus
IgE
Found in lungs, skin & mucous membranes; active in some allergies and parasitic infections; causes mast cells and basophils to release histamines; may occur in allergic reactions to milk, some medicines, and some poisons.
Functions of spleen
Largest lymphatic organ
Site of lymphocyte proliferation and immune surveillance and response
Blood cleansing functions: destroys aged or defective red blood cells and blood-born pathogens
Stores and releases components of hemoglobin
Stores platelets
Hematopoietic site in fetus
Ceases to function as this after birth

Helper T cells
Helper T cells are required for full activation of most B and T cells, activate macrophages, and release essential cytokines.
Function in the adaptive immune system activation
Critical cell in immunity
Cytotoxic T cells directly attack and kill infected cells and cancer cells.
Regulatory T cells help maintain tolerance in the periphery (prevent autoimmune reactions).
Immune response is enhanced by cytokines released by T…...

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